Drew Brees and Tom Brady enter Week 10 of the NFL's schedule neck and neck in closing in on matching Brett Favre for second place on the career regular-season list.
Brees has 506 touchdowns passing, two behind Favre, as the New Orleans Saints play at Cincinnati. And Brady has 505 with his New England Patriots playing at Tennessee. Both are a little more than 30 behind Peyton Manning's record of 539.
Brady does have chance to pass Manning on the career touchdowns passing list, including playoffs. Manning has 579, only three more than Brady.
On the other end of the quarterback matchup spectrum Sunday, the Buffalo Bills and New York Jets will feature a battle of the backups rather than far more intriguing AFC East showdown of two rookie first-round picks.
Matt Barkley is starting in place of Buffalo's Josh Allen, who will miss his fourth straight game with a sprained throwing elbow. For New York, Josh McCown is starting in place Sam Darnold, who is sidelined by a strained right foot. Darnold was drafted third overall, four spots ahead of Allen.